Researchers Look To Chinese Herbs To Treat Dog Cancer

by Lori Ennis

Published: September 27th, 2017

researchers look to chinese herbs to treat dog cancer

A cancer diagnosis for our dogs can mean a shorter lifespan. A Detroit, Michigan pet hospital is looking to use traditional Chinese medicine to treat spleen cancer.

A clinical study that began in August is looking to use traditional Chinese herbal medicine to treat dogs with spleen cancer in hopes of prolonging their lives. The study is working with dogs who have canine splenic hemangiosarcoma, which is typically treated by taking the spleen after the tumor has burst and bled. Sadly, the surgery could lead to blood loss that is life-threatening, and because the disease is so aggressive and the survival time after surgery is so short, many dogs only live up to two months longer anyway. The cancer just metastisizes too quickly.

Often chemotherapy is advised after surgery, but the researchers want to see whether or not Chinese herbal medicine protocols will prolong life after surgery of dogs who have no other cancer metasticizing. Dr. Erin Bannink will lead the study and says that they will use Panax notoginseng (San Qi) as the main ingredient in their trial formula. The ginsenosides shown antitumor activity, says Dr. Bannink. She also believes that herbal therapy can help with metastasizing of tumors because they are anti-inflammatory and anti-blood vessel formation.

Dr. Bannink believes that dogs who are treated with the herbal protocol after splenectomies will have better survival times and rates over those who only have splenectomies, and can give survival rates that are comparable or even better than others who have splenectomy and chemotherapy treatments.

Previously, the hospital has evaluated 14 dogs who had stage II splenic hemangiosarcoma and saw an average survival time of 253 days, along with a 36 percent one-year survival rate.

The study will be free to those who have dogs in the trial, and pet owners who are in the Michigan area and have dogs with stage II splenic hemangiosarcoma can volunteer their dogs by emailing info@ovrs.com.

Lori Ennis

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New research from the Virginia-Maryland College of Veterinary Medicine at Virginia Tech has shown promise for treating brain tumors in dogs, and may one day even be used to help humans! A study funded by the National Institutes of Health has produced data from clinical trials that show promising results when it comes to treating brain tumors in humans. The study is a collaboration between the College of Veterinary Medicine at Virginia Teach and the Thomas K. Hearn Brain Tumor Research Center at Wake Forest’s School of Medicine. Related: Researchers Look To Chinese Herbs To Treat Dog Cancer Currently, the researchers are looking at the safety of a new chemotherapy medicine and delivery methods when treating brain tumors in dogs, as they want to find a safe and effective use of the drug for use in future trials. Dogs and people have similar brains in many aspects, and researchers are optimistic that the data they’ve found and will find will be beneficial for the treatment of tumors in humans as well. Dr. John Rossmeisl is a professor of neurology and neurosurgery in the Department of Small Animal Clinical Sciences and said that though dogs are benefitting from this, the drug research is a pathway for use in human cancer treatment as well. A dog in the trial was originally diagnosed with a glioma brain tumor, and gave a survival of only a few months more. She was treated in the trial, which required her to stay at the vet hospital for six days. She had preliminary lab tests and exams done as well as a tumor biopsy. Once the biopsy was processed, she received chemotherapy drugs specially modified for her tumor, and they were delivered directly to her tumor. This chemotherapy drug is unique in that it works by destroying cancerous cells, and not normal brain cells. She went home the next day. Since March, she’s only been back twice–six weeks after her infusion and four months later for evaluation, exceeding the projected survival rate that was initially given upon diagnosis. More, her tumor has been significantly reduced. Dr. Rossmeisl says that based on the dog’s initial MRI, it appeared to have shrunk approximately 50%, and in the four-month follow-up, it appears as a teeny little spot, compared to what it once was. She will continue follow-up care every two to three months, and her owners are thrilled she was able to get the treatment she was. Related: New Antibody Gives Fresh Hope For Dog Cancer Treatment Dr. Rossmeisl said that there are different sub-types of gliomas, so not all dogs will respond the same. Some have lived for a year longer, with their tumor shrinking, while other dogs in the study have seen no difference. That said, this drug in previous generations of development have been used safely in human brain tumor studies and trials and he believes this information will apply to humans as well within the next five years. The trial began in 2014 and still accepts dogs for participation. They are happy with the positive outcomes they’ve had thus far, and believe there is more to come–for our best friends and for us.

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Camping Available at Best Friend's Animal Sanctuary

Are you searching for a pet-friendly camping solution for the upcoming travel season? If so, you’re in luck! Located in Kanab, Utah, the Best Friends Sanctuary offers a beautiful getaway for animal lovers.The location offers hiking trails, children’s activities, the Sanctuary store, the Angel Village café, and, of course, the animal sanctuary. Whether you plan on staying for a night or more, there are plenty of opportunities to enjoy your trip while making a difference for the most vulnerable.Located on 3,700 acres, it is home to up to 1,600 animals on any given day. The animals in their care include cats, dogs, birds, bunnies, horses, pigs, and others.There are 18 RV sites with 30—and 50-amp power, septic, and water hookups. Free Wi-Fi is also available to visitors. While the sites can accommodate larger RVs and trailers, any over 21 feet may have difficulty navigating the roads within the sanctuary, and it is recommended that these guests have a separate vehicle to get around during their stay.If you don’t have an RV, cottages and cabins are also available on-site. The most significant differences between these two options are the guest capacity and location. Cottages can accommodate groups of up to six, while cabins are designed for only one or two people. Unlike the cabins, which share a group patio area, each cottage has its own dedicated patio or deck.Visitors can reserve a tour of the sanctuary to see the beautiful views and the incredible work the organization is doing or sign up to volunteer. It’s the perfect opportunity for those who want to give back, dedicating a small portion of your vacation to helping around the sanctuary and leaving you with the good feeling of knowing you made a difference.You can schedule a volunteer shift up to a year in advance with tasks including:Walking the animalsPreparing and serving foodQuality time playing with or petting the animalsCleaning (dishes, mopping, etc.)Making toys or treatsGeneral maintenance and upkeep on the groundsThe minimum age for volunteering depends on the task, with the Bunny House and Parrot Garden accepting volunteers as young as eight.If camping isn’t your travel style, no problem. Five minutes down the road, you will find the Best Friends Roadhouse and Mercantile, a boutique pet-centric hotel. The location offers 40 rooms and suites, a complimentary vegan continental breakfast, an on-site pet grooming facility, and a dog park complete with a seasonal splash pad.With an allowed maximum of four pets per room and no pet fee, the hotel takes “pet-friendly” to a whole new level!Are you traveling without your pet and need to get your “fix” of cuddles and playtime? You can also host a sleepover with a dog or cat from the sanctuary at the hotel. Simply contact the hotel in advance to arrange for a furry sleepover guest.Of course, if you fall in love with an adoptable animal during your stay, you can always apply to add that furry (or feathered) friend to your family before leaving.Make your reservation to stay at the Best Friends Animal Sanctuary on their website today!Join the PetGuide community. Get the latest pet news and product recommendations by subscribing to our newsletter here.

How Cold is Too Cold for My Dog to Be Outside?

You might enjoy the magic of wintertime, but that doesn’t mean that your pooch shares your enthusiasm for cold weather – or the situation might be the exact opposite, with your four-legged bestie enjoying snowfall and you dreading the icy temperatures. Either way, you might be wondering if your pet needs some extra protection or different routines during winter – after all, some dogs are less suited for cold than others. So, it begs the question how cold is too cold for your dog, and should you even try going outside in these cases? There are several precautions you can take, but sometimes, you should be wary of extreme temperatures. Let’s delve deeper and learn more. How Cold is Too Cold for My Dog to Be Outside?The tolerance to cold weather can vary among individual dogs based on factors such as breed, size, coat type, age, and overall health. Generally, most dogs can tolerate cold weather to some extent, but there are certain conditions and temperatures where it becomes unsafe for them to be outside for extended periods. Of course, there will be some telltale signs that it’s just too cold to be outside. Signs that your dog may be too cold include shivering, whining, seeking shelter, lifting paws off the ground, or exhibiting signs of discomfort. If you notice any of these signs, it's time to bring your dog inside for some much-needed warmth.Of course, it’s essential to use your judgment and consider your dog's individual needs – you should always prioritize your dog's well-being in extreme weather conditions, but that will differ from dog to dog and climate to climate. Even so, there are some general guidelines for determining if it’s too cold outside for your pet – here’s what you need to know before taking them outside in really cold weather.Consider their coat length and breed: In winter, your pet’s coat can be a determining factor for outside time. Dogs with thick or double coats, such as  Siberian Huskies or  Alaskan Malamutes, may be more tolerant of cold temperatures than those with short coats, like Chihuahuas or Greyhounds. Some dogs were specially bred for living and working in cold environments, while some breeds were developed for completely opposite conditions. If your pet belongs to the latter group, it might be useful to invest in  a warm coat  designed to keep your dog toasty and warm during cold weather.

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Pet Obesity Study Shows Promise and Surprising Links With Humans

If you thought that your chubby doggo is incredibly cute, you might want to consider what’s hiding behind that adorable exterior.  Pet obesity is a real thing, and it is a major health hazard that many dogs experience in their lifetime. And, sadly, a lot of it is connected to improper care and diet. To show us just how big of a problem it has become, the latest study from the  Association for Pet Obesity Prevention revealed that in the U.S. alone, around 59% of dogs and 61% of cats were overweight or obese! However, recently conducted research shows that there might be a way to battle the obesity pandemic – with certain strains of probiotics that can help curb pet obesity, especially when dogs are in question. A research team from Seoul National University's Department of Agricultural Biotechnology, College of Agriculture and Life Science, conducted a study investigating the effects of probiotics on canine obesity. They discovered two strains that appeared to have weight-reducing properties in obese dogs. To assess the probiotic potential of these strains, the researchers employed a lifespan analysis using Caenorhabditis elegans, a genetic model known for its simplicity in genetic manipulation and shorter lifespan compared to other animal models. Their findings were detailed in a  paper published in the Microbiology Spectrum journal.Thanks to the positive outcome of this research, a new hope was discovered for doggos struggling with excess weight. The use of Caenorhabditis Elegans offers “interventions aimed at enhancing metabolic health in various mammals”, according to the research team. What is more, the effects could be applied to cats, humans, and other mammals, since C. Elegans “serves as a human homolog model”. In general, this whole study could prove to be beneficial to several animal species, as well as humans, making its significance multifold. However, the exact way that bacteria affects weight is not entirely understood. Even though some studies show that certain strains will slow weight gain, researchers were still unable to find a connection between bacteria and weight.Nevertheless, the study is proving to be a major leap forward when pet obesity is considered. There is plenty of potential in this study, and further efforts could change the way dog obesity is experienced – or possibly even root it out for good! 

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Study Finds Link Between Having a Dog and Girls' Physical Activity

A new study finds that having a furry companion at home could help promote healthy physical activity in children, especially young girls. According to research from the Telethon Kids Institute in Australia, getting a new dog or losing a furry companion is linked with a child’s level of physical activity. This new research shows that having a dog could help promote healthy movement behavior in children. The study's lead researcher, Emma Adams, highlights the positive influence of dog ownership on children’s activity levels, pointing to potential benefits that start from early childhood.“We saw a significant jump in daily physical activity in children whose families acquired a dog over the study period, while those whose families experienced the loss of a dog recorded a steep drop-off in activity,” added Adams.The research teams from Telethon Institute and the University of Western Australia followed 600 children aged between two and seven years old, over a three-year period to determine the impact dog ownership (or loss) has on physical activity levels.The results showed that getting a dog or losing a family companion is associated with significant changes in children’s activity levels. Surprisingly, young girls showed the most significant response.“The results were particularly noticeable in girls, with girls who acquired a dog increasing their light intensity activity and games by almost an hour a day (52 minutes).”“On the flipside, there was a marked drop in light intensity activity and games in girls who experienced the loss of a dog, with their activity dropping by 62 minutes a day,” said Adams according to Independant. Children wore accelerometers during waking hours for seven days at a time to measure sedentary time, screen time, and physical activity. Parents were also asked about their childrens’ activity levels. Half of the children participating in the study didn’t own a dog at any point during the study period, 204 children had a dog for the entire three years, 58 got a dog during the study period, and 31 children lost their furry companion during the course of the study.Data showed that girls who got a dog increased their light intensity activities and games by almost an hour a day (52 minutes). At the same time, girls who lost a dog experienced a decrease of 62 minutes a day in the same activities. Researchers observed that unstructured physical activity, such as walking with the dog or playing in the garden saw an increase for both boys and girls who got a dog during the study. “If we excluded dog walking and playing, there were no changes in the unstructured physical activity, so we could see the changes in physical activity were actually from the addition of those dog-related activities,” said Adams. On the other hand, children who lost their dog decreased their unstructured physical activity by 10.2 sessions a week for girls and 7.7 sessions for boys. “Regular physical activity from an early age is essential for children’s physical and mental health development, but few children or adolescents are meeting recommended daily levels. Our findings indicate that having a dog in the family could help promote healthy movement behaviors in children and reduce their short- and long-term risk of chronic disease.”Although this study discovered a positive link between dog ownership and increased physical activity Adams stresses that it’s not a call for everyone to get a dog. “It’s important to note that we’re not telling families to just go out and get a dog - having a dog comes with many responsibilities and won’t be right for everyone.”Instead, this study encourages dog owners to use canine companionship to increase physical activity. Join the PetGuide community. Get the latest pet news and product recommendations by subscribing to our newsletter here.

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When is the Best Time to Start Puppy Training?

Training your pet is a very important task as it will shape them into a friendly, obedient dog that’s a pleasure to be around. While it does require a lot of patience and effort, training your dog on time makes your life as an owner much easier and prevents a myriad of behavior issues and other problems down the road. Of course, it goes without saying that you should start training early, while your doggo is still a puppy. That is the time when they gladly soak up all the information and eagerly learn. But when exactly is the best time to start puppy training? You can’t do it while they are still teeny-tiny, nor should you wait too long. What is the ideal middle ground? Let’s find out.When is the Best Time to Start Puppy Training?Puppies are like sponges, soaking up information from their environment and their owner, so early training can set a solid foundation for good behavior and establish obedience throughout their lives. Ideally, you can start basic training such as housebreaking, socialization, and simple commands like "sit" and "stay" when your puppy is around 8 weeks old. This is the general “golden rule” that many owners stick by. When they reach that 2-month mark, it’s considered the ideal time for them to quickly grasp the commands you teach them. If you think that this could be “too early” to start training, you are wrong. There are numerous benefits to early training, and all of them are critical for your dog’s well-being and normal behavior. Here are just a few of them:SocializationEarly socialization is so important for puppies. It allows them to learn how to properly interact with other dogs and humans and prevents aggression and behavioral problems later in life. During this period you should expose your pet to new environments, sounds, and sights.BondingTraining sessions are a great way to strengthen the bond between you and your puppy. Spending time together, teaching them new things, and rewarding good behavior builds trust and a positive relationship.Preventing Behavioral IssuesIf you spot behavior issues while your dog is still a puppy, it is easier to prevent them from becoming nasty habits. As you teach your pet proper behavior and as you set up boundaries, you will prevent many nasty issues from forming, such as excess chewing, barking, or disobedience. If you already notice chewing issues that stem from teething, make sure to redirect their attention to an appropriate chew toy and use  puppy no-chew deterrent sprays to help you shift their focus.

A Xmas Miracle: Shelter Empty for the First Time in Nearly 50 Years

It was a very merry Christmas for a Pennsylvania shelter whose kennels were empty for the first time in nearly 50 years. Just two weeks ago, the shelter was packed with cats and dogs. However, the staff and volunteers have been working around the clock to make sure the animals in their care got adopted into loving homes. The Adams County SPCA is overjoyed that the shelter is empty, especially during the holidays.“This is the first time in 47 years that the Adams County SPCA is empty let alone on Christmas time, it is a true miracle!” the shelter wrote on Facebook. “To say that we are beyond excited is an understatement! The staff and volunteers have worked very hard to take care of the animals in our care and to make sure they got adopted into the right home.”The organization had a busy year, taking care of 598 animals before adopting them into furever homes. The hardworking staff and volunteers also reunited 125 stay animals with their owners this year alone.Adams County SPCA kennel technician Tanya Hays said that in the last two weeks, the shelter found homes for 20 animals, either as adoptions or strays returned to their owners.“We had to get them all spayed and neutered, vaccinated, and tested for heartworms and thick-born illnesses while also processing a lot of (adoption) applications, so the staff worked really hard,” said Hays to TODAY.“It was pretty cool. It was quite a feat,” she added.The organization took to Facebook to thank their community. “Our community stepped up once again! We thank everyone for their continued support and look forward to new adventures in 2024!”Although it may seem like people are more motivated to adopt animals during the holidays, the shelter actually discourages people from giving pets as gifts because these animals are more likely to be returned to the shelter weeks later. While the staff and volunteers celebrated everything they achieved this year, they are already ready to get back to work. “We will be pulling animals from other shelters in Pennsylvania next week in hopes of relieving some of their stress,” the shelter shared. “Right now we are going to enjoy this accomplishment!”In a follow-up post, the organization shared that it has “received an overwhelming response” from different shelters across the country and also from Canada and Mexico. Members of the public have also reached out asking them to take in abandoned animals. “Even though our hearts break for them and the situation they are in we need to help the members of our community first,” the organization said. The Adams County SPCA is only taking animals from overwhelmed shelters in Pennsylvania and animals surrendered by residents within the county as well as those living in surrounding counties. “We are going to do the best we can to help as many animals and people we can.” Join the PetGuide community. Get the latest pet news and product recommendations by subscribing to our newsletter here.

Guinness World Records Reviews Bobi’s 'World's Oldest Dog' Title

A Portuguese dog named Bobi made news last year when Guinness World Records crowned him as the world’s oldest dog. Bobi was 31 years and 165 days old when he died at his home last October.However, Guinness World Records has now suspended Bobi’s title after complaints made by veterinarians and professionals questioning the legitimacy of his age.Bobi, who was a purebred Rafeiro do Alentejo, was also declared the world’s oldest dog ever, breaking a nearly century-old record held by an Australian cattle dog, named Bluey, who died in 1939 at the age of 29 years and 5 months. The average life expectancy of a purebred Rafeiro do Alentejo is 12 to 14 years.A spokesperson for the Guinness World Records explained that the review into Bobi’s record is ongoing and it includes looking over the evidence again, looking for new evidence, and talking to experts and all those linked to the original application. “While our review is ongoing we have decided to temporarily pause both the record titles for oldest dog living and (oldest dog) ever just until all of our findings are in place and have been communicated,” said the spokesperson, according to CBS News.Several skeptics pointed out that Bobi’s feet appear to be of different color in photos of him as a puppy and in recent pictures of him in his old age. A Lisbon vet, Miguel Figuereido said last year that Bobi doesn’t really look like a very old dog with mobility problems and an old dog muscle mass. Additionally, an investigation by Wired discovered that Bobi had been formally registered on Portugal’s pet database in July 2022. Leonel Costa, the dog’s owner, registered Bobi as being born in 1992, but there hasn’t been any proof, other than the owner’s word. According to Portuguese law, dogs born before 2008 didn’t have to be registered until October 2020. The Portuguese database for dogs, cats, and other pets also told Wired that they weren’t contacted by Guinness World Records to verify the information. Many other veterinarians and canine experts have questioned Bobi’s true age in correspondence to the Guinness World Records. A veterinarian and council member of the Royal Colledge of Veterinary Surgeons, Danny Chambers, told the Guardian, “Not a single one of my veterinary colleagues believe Bobi was actually 31 years old.”Guinness World Records insists that the suspension is temporary while the review is ongoing.Bobi spent his whole life living with the Costa family in the village of Conqueiros, in Portugal. The pooch, who was allegedly born on May 11, 1992, escaped death in his first days of life. Bobi, along with three other puppies, was born in a woodshed belonging to the Costa family. But, because they already owned many animals, the parents decided to get rid of the newborn puppies.One puppy - Bobi - was unintentionally left behind and discovered days later. Bobi’s owner, Leonel Costa, who was eight, and his sister persuaded their parents to keep the pup, and so he remained living with the family.Leonel Costa defended Bobi’s title saying that “an elite within the veterinary world…tried to give people an idea that Bobi’s life story was not true.”Costa believes this happened because he attributed Bobi’s longevity to a varied diet of human foods, rather than pet food. He said this goes against the recommendations of many veterinarians. “Everything would be different if we had said he (Bobi) ate pet food for three decades,” said Costa, adding that they’d provided everything Guinness World Records requested to validate Bobi’s age. Bobi has never been chained up or put on a leash and used to roam the woods around the village until he got too old to move much. He spent his golden years lounging in the yard with the family cats. Join the PetGuide community. Get the latest pet news and product recommendations by subscribing to our newsletter here.

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