What is Hemolytic Anemia in Dogs?

by Kate Barrington

Published: September 15th, 2018

Although your immune system is supposed to protect you, in some cases, it can have the opposite effect. That’s what can happen if your dog has hemolytic anemia.

As you may already know, anemia is not actually a disease but a symptom of it. A medical term referring to a reduced number of red blood cells (RBCs), anemia has a number of different causes. Hemolytic anemia, also known as autoimmune hemolytic anemia, is the result of the immune system attacking and destroying healthy red blood cells and it can become very severe or even life-threatening. Keep reading to learn more about what hemolytic anemia is and how it can be treated.

What Are the Causes and Symptoms?

In dogs, autoimmune hemolytic anemia can be either primary or secondary – when it is primary it is also idiopathic, or it has no known cause. The dog’s immune system malfunctions and incorrectly produces antibodies that attack the dog’s own red blood cells. An estimated 75% of cases of hemolytic anemia in dogs are primary. Secondary hemolytic anemia is indirectly caused by an underlying disease or toxic damage that causes the surface of the red blood cells to become altered. The altered blood cells then become the target of the immune system and they are destroyed.

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One of the most common symptoms for hemolytic anemia in dogs is pale gums – this is in contrast to their normal pink to red coloration. Many dogs with anemia will appear lethargic or listless and they may tire more quickly than usual. Because there are fewer blood cells to carry oxygen throughout the body, the dog may also faint or become confused as a result of poor oxygen levels in the brain. In order to compensate for low oxygen levels, the heart may beat more quickly, and the dog will breathe more rapidly. As the disease progresses, by-products of RBC breakdown will accumulate in the urine, causing it to develop a dark yellow color.

How is Hemolytic Anemia Typically Treated?

Hemolytic anemia is fairly simple to diagnose – all you need is a blood test called a complete blood count (CBC). One specific aspect of the test, the packed cell volume (PVC) or the number of red blood cells, is used to diagnose hemolytic anemia. If the results of the test suggest anemia, your vet may then perform additional tests to determine whether the condition is primary or secondary.

From there, more tests may be required to identify the underlying cause of the issue. The results of these tests will inform your veterinarian’s decision when it comes to treatment. If your dog’s anemia is very severe, however, your vet may recommend a blood transfusion to stabilize his condition while other tests are run. In cases where no obvious cause can be determined, immunosuppressive drugs may be the only option to stop the destruction of red blood cells and improve your dog’s condition.

Hemolytic anemia is not an immediately life-threatening condition, but it can certainly progress to that point. If your dog appears listless or tires too easily for no apparent reason, take him to the vet. It is not worth taking the risk when these issues could be signs of a serious problem.

Kate Barrington

Kate Barrington is the loving owner of two cats (Bagel and Munchkin) and a noisy herd of guinea pigs. Having grown up with golden retrievers, Kate has a great deal of experience with dogs but labels herself a lover of all pets. Having received a Bachelor's degree in English, Kate has combined her love for pets and her passion for writing to create her own freelance writing business, specializing in the pet niche.

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You’ve probably noticed how your four-legged bestie influences your mood for the better, but did you know that your pet might be beneficial to your brain? That’s right! The latest studies show that your pet and their company could be just the thing to lower the risk of dementia in your golden years. These findings are especially important for single senior pet owners who are at risk of this troubling illness as they reveal that having a pet can make a drastic change. A recent study that involved adults over the age of 50 who lived alone revealed that those living in the company of a loved pet will have considerably less decline in their verbal fluency and verbal memory - compared to those who lived without a pet. This research was published in the  journal JAMA Network Open and was based on data taken from 7,945 people in the mentioned age group.This study, however, only reflects on people who live alone and does not involve participants who lived with other persons in the household. Still, while the results reinforce the fact that loneliness is a major risk factor for cognitive decline and dementia in old age, they also reveal something new – that the company of a pet counts as much as the company of human family members, if not more so.The early signs of cognitive decline can be fluency, verbal issues, cognition, and memory problems, and so on. But if you have the company of a pet, whom you can address and care for, can greatly reduce the feelings of loneliness and keep these cognitive issues at bay. This study and its results are very important in today’s day and age and for many Americans in particular. Recent U.S. Census Bureau insights revealed that almost 28 percent of all households in the United States were “one-person households” in 2020. This is an alarmingly large number and shows us that many people aged 50 and older will face lonely senior years. Of course, even though the results of this study show that older people can maintain their mental health through the company of a pet, the research team emphasized that more advanced studies and clinical trials will be required to fully confirm the results. Yet even so, the lack of an effective therapy that can reverse or slow cognitive decline and treat dementia means that these results are a small but very important benefit for the understanding of these issues. And, needless to say, all those who are entering their senior years and want to spend them in a healthier and more beneficial way now know that their next station should probably be a local pet shelter. Find a pet you can love and cherish - and keep your brain healthy while showering them with affection.

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Scientists Uncover Secrets of Extinct "Wooly Dog" Breed

Throughout history, dogs have played several key roles in the lives of people globally. They have hunted, worked, and provided for us, forever weaving them into the fabric of human existence. We often use this knowledge to better understand our modern dogs by reflecting on their original purpose as a breed. Unfortunately, not every breed continues to thrive among us today.The Coast Salish wooly dog was a unique breed, kept by the First Nations people throughout the Pacific Northwest, including Vancouver Island, for its fleece-like coat. A new study reveals insights into the history of the now-extinct breed.Unlike most animals at that time in history, the dog was kept in pens and longhouses. This was done to prevent the dogs from mixing with village and hunting dogs, preserving the breed and the fleece it provided.“They were sheared like sheep, and the wool was woven into blankets,” recounted Eliot White-Hill of the Snuneymuxw First Nation. “Blankets were like currency in our economy prior to contact and some of the most important things you could own and give away as gifts.”The dogs were fed a diet of fish and elk and were seen as beloved family members.“It’s not just a dog – it’s a relative. It has enormous spiritual power, conveyed in its wool,” explained Michael Pavel, an elder of the Skokomish-Twana tribe and one of the study's authors. “Imagine being able to receive the gift of wool fiber, being able to learn to weave that into yarn, into an entity, or a blanket or robe that you could wrap yourself in the coldest of winter and feel the warmth of those prayers. That’s how we look at it, and we can now enjoy a scientific view, as well.”Unfortunately, the breed did not survive colonization. It’s not clear exactly what caused the demise of the Coast Salish wooly dog – the introduction of European dog breeds, rules enforced on First Nations people during assimilation and displacement, or smallpox epidemics being a few of the hypothesized factors.But thanks to the preserved pelt of a wooly dog named Mutton, who died in 1859, researchers can now learn a little more about the unique DNA of the dog, its lineage, and insight into the breeding practices of local Indigenous communities.Researchers compared DNA from Mutton’s pelt to that of a separate non-wooly village dog that lived and died in the same region at approximately the same time.While the information gathered from the study did not offer any conclusive answers about the disappearance of the breed, it did hypothesize that the Indian Act of 1876 played a critical role as it would have directly impacted the ability of Indigenous women to pass on valuable knowledge about caring for the dogs and weaving necessary to its survival.On a positive note, the study did support historical facts shared by First Nations people in that area – a valuable piece of the puzzle as many work to reclaim the traditions of their ancestors.“It brought a large group of people together that reaffirmed for us the history we know,” stated Violet Elliott, also of the Snuneymuxw First Nation. “It was a gift of collaboration with other nations.”

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Study Finds Pet Parents Care More About Their Dogs Than Their Cats

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How Much Exercise Does My Cat Need?

Cats are often known for their laidback and aloof personalities, lounging around the house like true couch potatoes. But just like us, our kitties need regular exercise to live a happy, healthy, and fulfilling life. That’s where your job as a cat parent comes in! In this article, we will explore the importance of exercise for your cat, including how much exercise they need, the benefits of being active, and fun ways to include more physical activity in your cat’s daily routine. Whether you have an energetic young kitten or a calm senior cat, understanding their exercise needs can make a significant difference in their overall well-being. How Much Playtime Does an Indoor Cat Need? When choosing the perfect pet for your family, you have likely heard about how laid back and easy to care for cats can be. After all, they just lounge around the house all day. Right? The truth is that your cat needs daily activity to stay healthy and in shape. The exact amount of exercise your cat needs will depend on several factors, including their age, breed, lifestyle, and individual health needs. For example, a cat that is obese and needs to lose weight to improve their health may need more physical activity than a cat that is already of a healthy weight. That being said, the general rule of thumb is that a healthy adult cat should be engaging in 30 to 60 minutes of active playtime every day, split into shorter 10 or 15-minute play sessions. If you are unsure about your cat’s specific needs, contact your veterinarian. They will be able to provide insight into how exercise and playtime can improve or help to maintain your cat’s quality of life at this stage and as they continue to age. How Do I Know My Cat is Getting Enough Exercise? There are several behavioral signs that a cat isn’t getting enough exercise that you can watch out for. Cats that don’t engage in regular physical activity often suffer from boredom, depression, or anxiety. While our cats obviously can’t speak to tell us this, we can pay attention to their body language and behavior to catch any signs of trouble. Some key signs to watch out for include: Destructive Behavior: One of the first signs people notice when a cat is bored is that they start to exhibit bad habits and destructive behavior. This could include scratching your furniture, tearing apart the toilet paper, ripping curtains or screens, or stealing items they know they shouldn’t. It’s like a young child. They are bored and looking for ways to keep themselves entertained. Excessive Vocalization: Do you have a naturally vocal cat? If so, they may be trying to tell you that something’s wrong verbally. Some cats, when bored, will cry out for attention. This is a behavior we see in our two every time their morning playtime is even 5 minutes late. Change of Appetite: If they are feeling anxious or highly stressed, some cats will stop eating. Others, like humans, will turn to food during times of boredom. Any unexplained changes to your cat’s diet should be considered a sign of trouble – whether it’s a need for more exercise or something health-related.Over-Grooming: Cats are masters of self-grooming, but if a cat is stressed, anxious, or bored, they may take their grooming too far. This can often lead to the development of bald patches or skin irritation. Aggression or Irritation: Some cats become irritable or upset when experiencing stress and anxiety. This could result in uncharacteristic biting or scratching directed towards you, other family members, or other pets in the home. Loss of Energy or Lethargy: This may come as a surprise as most people will associate not enough exercise with having pent-up energy just begging to come out. However, a cat that isn’t getting enough physical activity can become depressed, which may present as being lazy, uninterested, or more aloof than usual. Another important sign to watch out for is unexplained weight gain. Just as humans will gain weight if they aren’t getting enough exercise, so will your cat. Sure, they likely aren’t concerned with “how they look” each morning – but obesity is a growing problem in the United States and can introduce serious health consequences!

BARK Air Introduces a New Flight Tailored for Dogs

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Keeping aquarium fish is such a rewarding experience, but that doesn’t mean it’s always easy to do so – there are many things to know about these wonderful creatures, and caring for them can require a lot of patience and plenty of learning. Of course, it all starts with the basic stuff, and it doesn’t get more basic than feeding your pet! A common question by pet fish owners is related to feeding frequency, as their aquatic friends can’t really let them know when they are hungry. So, without further ado, here’s how often should you feed your fish depending on their unique characteristics.How Often Should I Feed My Fish?There are a lot of factors that will determine the feeding schedule you have for the inhabitants of your saltwater or freshwater aquarium. The frequency of feeding your fish depends on the type of fish, their age, and the specific conditions of your tank. Adult tropical fish are most commonly fed once or twice a day. You can feed them a small amount of food that they can consume within a few minutes. Cold-water adult fish, on the other hand, such as  goldfish, can be fed two or three times a day. In any case, be cautious not to overfeed as it can lead to water quality issues.Young fish, however, may require more frequent feeding, at least three times a day, because they are still growing rapidly. Of course, some specific types of fish have equally specific dietary requirements. Research the particular needs of the species you are keeping to ensure you are providing the right type and amount of food. Your local pet fish store can also provide guidelines, as can your vet. When you are feeding your fish, it is important to stick around and observe them, at least initially. Paying attention to your fish during feeding can provide you with plenty of information. If they consume all the food quickly, you can consider increasing the amount slightly. If there is uneaten food after a few minutes, you may be overfeeding. Try to find that perfect balance. Another thing to consider is the so-called “fasting day”. This means not giving your fish any food for a period of 24 hours – and don’t worry, this won’t harm them. It's a good idea to incorporate a fasting day into the weekly routine. This helps mimic their natural feeding patterns and allows their digestive systems to rest. Most aquarists fast their fish for one day of the week, which is more than enough for your fish to reap the benefits.How Much Food Should I Give My Fish?A good rule of thumb is to always give less food than you think your fish need – and add more additionally throughout multiple feedings during the day if needed. Remember that overfeeding can lead to poor water quality as uneaten food breaks down and produces waste. It's crucial to maintain a balance and not exceed the recommended amount. In such cases, it is good to have a  special aquarium water quality monitor, which can tell you the key information about the water in the tank. Additionally, some fish species are more active during certain times of the day, so adjusting feeding times to coincide with their natural behavior can be beneficial.

Study Reveals the Most Expensive Locations for Pet-Friendly Airbnbs

Are you considering taking a trip to a dream destination in the United States with your best friend by your side? If so, you’re not alone! A growing number of animal lovers are taking steps to include the whole family in their travel plans, with Airbnb reporting that close to 50% of nights booked include pets. But have you ever stopped to consider how much your furry family member is increasing the budget?The team at MarketWatch recently released a guide to pet-friendly Airbnb travel in the US with some startling stats.Data was compiled about the cost of renting 11, 676 Airbnbs and 11,753 pet-friendly Airbnbs located in 46 of the most popular tourist destinations in the United States. By comparing the average nightly cost for pet-friendly and pet-free locations, they determined the price premium or the added cost pet parents must pay to include their furry friends.While we’re not suggesting that the cost of accommodations should be the sole deciding factor for your next vacation, this could impact your top choices.According to the guide, the most expensive city is Honolulu, Hawaii, with an average night stay costing $511. This is also the destination where pet parents will face the highest price premium for booking a pet-friendly location at $345.50.If you’re an avid traveler, this likely comes as no surprise. Hawaii is one of the country's more popular destinations for luxury travel. Not only is the cost of living in the state one of the highest, but the state also charges a Transient Accommodations Tax (TAT), further increasing costs.Of the 10 most expensive tourist destinations to book a pet-friendly Airbnb, 7 were in California. In addition to Honolulu, the list includes:Monterey, CA ($509)Sonoma, CA ($488)Napa Valley ($380)Santa Cruz, CA ($339)Palm Springs, CA ($329)Boston, MA ($238)Los Angeles, CA ($226)San Francisco, CA ($226)Yellowstone National Park, WY ($219)Don’t let these costs keep you from planning your next big pet-friendly getaway. Not only did they compile a list of the most expensive destinations, but they also identified the least expensive nightly rates in the US. This list is a great way to travel with your pet without worrying about your budget.They discovered that the least expensive city to book a pet-friendly Airbnb is Oklahoma City, OK, where the average nightly rate is only $110. Other locations that made this list include:St. Louis, MO ($111)Cleveland, OH ($114)Columbus, OH ($117)Houston, TX ($119)Salt Lake City, UT ($119)Detroit, MI ($124)Memphis, TN ($125)Indianapolis, IN ($129)San Antonio, TX ($130)Booking a lower-cost Airbnb is only one of many ways to keep the costs down when traveling with your pet. Pack all your pet’s travel essentials before your trip, including a leash, food/water dishes, grooming supplies, plastic waste bags, and a first aid kit. If you are driving to your destination, you can also pack your pet’s food to avoid shopping for it once you arrive. You can gather these items by shopping local sales rather than paying a premium to get what you need on short notice. Pet Insurance is another great budget-friendly travel tip. This may seem counterproductive, adding the monthly cost of your pet’s policy to your budget. But if disaster strikes, the insurance policy can help to significantly reduce emergency vet bills.Whatever your budget, we encourage all pet parents to get out and explore, making memories with their pets by their side. You won’t regret it!Join the PetGuide community. Get the latest pet news and product recommendations by subscribing to our newsletter here.

Family Dog Alerts Parents to a Teen’s Stroke and Saves His Life

Dogs are so deserving of their title – man’s best friend - and they continue to prove it day in and day out. From being our best friends to providing irreplaceable acts of service to people in need, there’s so much that dogs do that makes a difference and this story only proves it.The fateful event took place in Spring, Texas, where the family Tanner lives, alongside their precious pooch, Axel. Axel is a 1-year-old  border collie, a rescue that quickly became a cherished member of the family and, as life would have it, their savior. It was around 5 am on a calm Saturday morning when Axel – completely out of the ordinary – jolted Amanda and her husband from their sleep. And it was no regular attention-seeking behavior. Something was amiss, and Axel was determined to let the couple know.“He was pawing me more than normal to get me to move,” Mr. Tanner explains for  Today.com. Realizing that the dog was clearly trying to wake them, Amanda’s husband went downstairs to check on things and let the dog outside. Axel refused. It wasn’t the outdoors he was seeking - there was something else. He quickly stopped in front of the closed doors of the 17-year-old Gabriel Tanner. Mr. Tanner went inside to check up on his son but realized what was the cause of the dog’s panic. Young Gabriel was having a stroke, his speech was slurred, and he could not feel his right side. At once they rushed him to the emergency room at the Memorial Hermann the Woodlands Medical Center. Young Gabriel was quickly treated and made a recovery. Dr. Sabih Effendi, who treated him, says that “by waking the parents up, and leading them to the boy, the dog made a “massive” difference in Gabriel’s outcome”. “It’s very amazing that their dog alerted and started this whole process of getting everyone awake and going downstairs,” Effendi continues. “When somebody’s acutely having a stroke, the neurons are dying. … If he was not found and another three or four hours went by, there would have been more and more and more brain injury.”The Tanner family is extremely grateful to have had Axel by their side in this crucial moment. They can only wonder what would have happened if the dog wasn’t there. He practically saved Gabriel’s life. “We wouldn’t have thought to go into Gabriel’s room and wake him up. He’s a teenager. It was a Saturday morning. We went to bed late. We wouldn’t think to go in there until maybe noon,” Amanda says.Nowadays, Axel is a precious member of their family and tends to follow Gabriel wherever he goes. He also sleeps with the teen a lot more, always on the lookout for anything out of the ordinary. A true four-legged friend and proof that dogs can be loyal to no end! 

New Survey Ranks America's Top Dog Breeds by State

There’s no doubt about it - Americans love their dogs! We know that your pooch is the best breed, but have you wondered which are the most favored dog breeds in America? Forbes surveyed 10,000 dog owners across the 50 states to find America’s top dog breed. The survey involved the top 25 most popular dog breeds nationwide, according to the American Kennel Club. So, what is America’s top dog? As it turns out, “no breed in particular” is the country’s favorite at 13%.However, if Americans had to decide, they’d pick the Australian shepherd as a favorite, followed by the German shepherd and the bulldog.The highly intelligent and energetic Australian shepherd was ranked as the top dog breed in 10 states, including Alabama, Arizona, Alaska, Arkansas, Georgia, Indiana, Montana, Missouri, New York, and Virginia. This breed was also voted the second favorite in nine states. Although Aussies won the popularity vote, the German shepherd was the number one pick in 16 states. That’s more than any other breed!Known for its loyal and courageous nature, the German shepherd is the most common breed to serve as a police K9 but also makes a wonderful family companion. They ranked as the second favorite dog breed in nine states. Interestingly, more men than women picked German shepherds as their favorite breed (9% compared to 6%). America’s 3rd favorite breed, according to Forbes, is the bulldog. The English bulldog is a medium-sized dog breed, best known for its stocky build, large head, and wrinkled face. The bulldog ranked as the top dog in eight states, including Illinois, Connecticut, Missouri, Mississippi, North Carolina, South Carolina, West Virginia, and Utah. Among all states, Nebraska ranked the bulldog lowest, placing this breed at 24th place, The lovable and friendly Labrador retriever ranked as the nation’s 4th favorite breed. Thanks to their affectionate, friendly, and energetic nature, Labs make great companions to people of all ages and families with children. Labrador retrievers ranked as the most favorite dog breed in 10 states, including Louisiana, Idaho, Minnesota, Montana, Massachusetts, Nebraska, New Hampshire, Oregon, South Dakota, and West Virginia. Bernese mountain dog is the 5th favorite dog breed in the United States. Large in size and built for hard work, Bernese mountain dogs are easy to train and make affectionate, loyal, and faithful companions. So, it’s no surprise that this doggo ranked as the most favorite breed in nine states. Compared to four other top-ranked breeds, the Bernese mountain dog had the most varying results, with 10 states ranking this breed in the bottom 10.The beagle is the nation’s favorite small breed. Ranked as the 6th favorite breed overall, the beagle was placed in the top 10 favorite breeds in all but seven states. This breed received the lowest ranking in Utah, where it was voted as the state’s 3rd least favorite breed.The golden retriever comes in at 7th place, after being voted as the most favorite dog breed in Michigan and Wisconsin. Medium in size and best known for their gorgeous golden coats, golden retrievers are loving, loyal, and affectionate companions to active people and families with children. Goldens were the 2nd favorite dog breed in four states, including New Hampshire, North Dakota, Connecticut, and Vermont. This breed ranked the lowest in Alabama, where it received 17th place.These are America’s most favorite dog breeds, but the nation also has the least favorite doggo. This title goes to the Havanese, which was the bottom-ranked breed in 33 states.The Havanese is followed by Pembroke Welsh Corgi which was the least favorite dog breed in 17 states. And what about you? What’s your favorite and least favorite dog breed?Join the PetGuide community. Get the latest pet news and product recommendations by subscribing to our newsletter here.

Great Dane Sets the Largest Litter Record at North Carolina Rescue

A North Carolina dog gave birth to a litter of puppies and has set a record in the process. Earlier this month, Perfectly Imperfect Pups, a North Carolina foster-based rescue took in a pregnant Great Dane, named Meadow. Two days later, Meadow gave birth to 15 puppies. “It’s the largest litter we have ever seen,” said Nicole Kincaid, the rescue’s founder and director. “We could not believe it when we heard she had 15 puppies, and most of them male! We are so excited for their bright future!”Meadows litter is the largest the rescue has seen since it was founded three years ago. The PIP’s founder and director, Nicole Kincaid, shared that this is also the largest litter she has seen in her 13-year-long rescue career. According to Kincaid, Meadow’s litter is unique for another reason - most of the puppies in the litter are male. “Shockingly enough, we have 12 boys, which is a huge number of boys out of a litter.”PIPs share the news of the record-breaking litter in a Facebook post, writing, “Puppies, puppies, and more puppies! Mamma Meadow and her crew are doing great.”“We are shocked to find out how many puppies she actually had and that all have survived and are doing well,” said Kincaid, according to PEOPLE. “Before being taken in by the Perfectly Imperfect Pups, Meadow had an unsteady past. “She has been passed around to five homes, since giving birth to another litter in February. She was being given away on social media and we reached out, but unfortunately, they gave her away pregnant to someone else.”“Within two days they contacted us and asked if we could still take [Meadow], and of course, we were delighted to take her in,” Kincaid shared. “We got her to our vet the next day, and the day after, she started going into labor.”Meadow is just one of many dogs who had the misfortune of being bounced around from one home to the next. Kincaid shared that this wasn’t Meadow’s fault, saying, “People get a large breed dog, and they don’t realize what they are getting themselves into.”“We are delighted that this will be her final [litter], and her next home will be her forever home,” said Kincaid. “We will also make sure that all 15 puppies go to homes that are experienced with large breed dogs.”For now, Shari Willson, one of the Perfectly Imperfect Pups’ fosters is taking care of Meadow and her pups. The foster mom is supplement feeding the pups in between feedings to make sure all puppies are getting enough food. “Everyone’s gaining weight, everyone’s eating, they are all doing really well,” said Willson.Kincaid praised Meadow’s foster home, saying that her organization “is so proud of our foster parents. They take in dogs without knowing what the next few days or months could bring.”“Taking in a pregnant dog is even more of a challenge because you don’t always know when mom will give birth, how many puppies will be born, or what complications may come along,” she said.The rescue has already received applications and hundreds of messages about adopting Meadow or her puppies when they are old enough to go to their forever homes. All of PIP’s adopters sign a contract in which they commit to taking care of the dog for its entire life and promise to contact the rescue if they can no longer care for them. The rescue’s post-adoption team follows up with the adopters and is available to answer any medical or training-related questions. Mamma Meadow and her pups are going to make wonderful companions and loving dogs to their new families! Join the PetGuide community. Get the latest pet news and product recommendations by subscribing to our newsletter here.

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