Best Melatonin for Dogs

PetGuide logo

While most dogs are happy-go-lucky furballs whose tails seem never to stop wagging, it doesn’t mean that they don’t experience stress and nervousness as we do. Pooches can be scared and stressed out in certain situations (such as during storms and fireworks, or visits to the vet’s) or are wary and fearful as a rule, often due to past trauma- this is often seen with rescue dogs that have been abused. Some dogs are more prone than others and develop serious anxiety issues that require medication, behavioral therapy, and lots of patience and effort from their pet parents. Needless to say, there are many different approaches to the problem of canine anxiety, whether situational or chronic and what works for one dog might not work for the other. It takes time and experimenting to get results, but going the tried-and-true route is always the safest bet. For instance, many pet parents swear by melatonin for dogs and its soothing effect it has on dogs in times of duress.

Melatonin for dogs is a supplement that boosts levels of the sleep hormone your pet naturally produces in order to calm your pet. Even though dogs produce melatonin naturally, the low-dose supplementation increases the level of this hormone just enough to make your dog relax, but giving too much is not a good idea. There are potential side-effects to melatonin for dogs, and it’s crucial to give it to your pet carefully- and only after your veterinarian has given you green light to rely on this supplement for treating your dog’s anxiety. Usually, when given properly and responsibly, melatonin for dogs can be a great solution for pets with separation anxiety or severe reactions to triggering situations (loud sounds, car rides, etc).

Of course, choosing the right type of melatonin supplement for dogs can be difficult- after all, there are so many to choose from! From pure melatonin supplements to formulas that include melatonin and other stress-relieving substances for a well-rounded effect, you’ll have your hands full when you try to narrow down your choice. To help you pick the best product for your pet’s needs, we’ve rounded up the best melatonin for dogs on the market. Read on to learn more about how this anxiety supplement is used and how to know which will work best for your nervous pooch!

Specially formulated for dogs, this supplement contains 3mg of melatonin per serving- which is more than enough to get your pet relaxed before a stressful event such as fireworks or visits to the groomers. As a chewable tablet with peanut butter flavor, this supplement is not difficult to administer: most dogs will see it as a treat! In case your dog suffers from chronic anxiety, has trouble sleeping or other issues that require regular use of melatonin, this dosage would translate into two chewable tablets per day if they weigh less than 30 pounds, and double that if they weigh more. 

Shop Now

It’s not easy keeping canine anxiety under control, but this potent calming supplement can certainly help minimize your dog’s symptoms. In addition to melanin, which contributes to the anti-anxiety properties of this formula, it also includes other powerful calming substances for dogs, such as L-Theanine (in Suntheanine form), organic ginger root, L-Tryptophan, organic hemp, organic passion flower, and chamomile. Together, they help sensitive and anxious pooches feel at ease in stressful situations and can soothe dogs with aggressive or hyperactive tendencies. This melatonin supplement comes in the form of turkey-flavored chewables, so your pooch is bound to love it.

Shop Now

If your pet is a picky eater or just gets fussy when you try to give him a tablet – no matter how good it smells- liquid melatonin supplement is the way to go. You can just mix in a few drops of it in your pet’s meal or some plain yogurt and they’ll be none the wiser – and still reap the benefits this calming substance offers. The best part is that this form of melatonin supplement is no less potent than most tablets and chewables on the market – one drop contains 3mg of melatonin.

Shop Now

In case your pooch gets nervous when he needs to ride in the car or during storms, for instance, just give him the recommended dose of these flavored chewables before the triggering event and watch them enjoy a stress-free experience for a change. The secret is in the powerful formula that includes melatonin, thiamin, L-Tryptophan, and ginger root that will soothe an upset stomach (ideal for motion sickness, too!). 

Shop Now

Combining nature and science, Dr. Lyon’s calming supplement is designed to offer maximum potency with a gentle, dog-safe formula based on natural ingredients. To make sure your pet is calm, especially in stressful situations, the formula relies on melatonin, thiamine, and l-tryptophan, as well as relaxing herbs such as chamomile and ginger that calms an upset tummy. The supplement comes in the form of soft chewables with chicken liver flavor – your dog will love them!

Shop Now

In cases where anxiety is severe, or the disrupted sleep patterns, skin issues, or Cushing’s disease require a stronger dose of melatonin, you’ll have to go for a more potent formula. Made with human-grade melatonin, these tablets contain 6mg of sleep hormone per serving and will ensure your dog gets the most out of the supplement – however, you should be aware that this supplement comes in the form of vegetarian capsules and it might be difficult to get your pet to swallow them unless he’s trained.

Shop Now

If you’re looking for something to help your pet grow his hair back, or don’t need a potent calming aid, these soft chews are a good match. With 2m of melatonin per serving, they’ll help maintain a healthy, shiny coat with thick hair – not a bald spot in sight. To boot, this supplement is also safe for cats to use- so a big plus if you have a multi-pet household!

Shop Now

Calmify offers all the benefits of the sleep hormone just in the more convenient liquid form. Not unlike most melatonin supplements for dogs on the market, this one also delivers a dose of 3mg of melatonin per serving – which allows you to adjust according to your pet’s size. Squirt out the suggested amount of liquid in your dog’s wet food or over their kibble and ensure they get the help they need without the additional stress that administering supplements can become. 

Shop Now

These calming dog chews come from the company that created Thundershirt for dogs and has a rep of having the best aids for anxious pooches. Needless to say, they’re quite popular with pawrents and pets alike! The formula unites melatonin with other nerve-soothing ingredients such as thiamine, L-Tryptophan, ginger, passion flower, and chamomile. The combination is ideal for treating chronic anxiety and situational anxiety both. 

Shop Now

For those dogs whose sleeping patterns are more of a concern than their anxiousness, this supplement is ideal: it’s specially formulated to help your dog’s sleep disturbances. Whether it’s regulation of the sleep-wake cycle or reducing nighttime waking up, this supplement promises to help. The 3mg of melatonin per serving will put your pooch in a mood for a nap, and additional calming substances such as organic valerian root, organic passion flower, organic ashwagandha, and many others will make him feel at ease and stress-free. 

Shop Now

The formula of these calming treats helps manage your pet’s stress – whether it’s separation anxiety, situational anxiety due to loud noises or past trauma, or just regular nervousness on car rides and visits to the vet, the soothing ingredients in these chews can help. With 2mg melatonin in the mix, they are not among the most potent on the market – but can be a great solution for small breed dogs. The effects of melatonin are boosted by other anti-anxiety substances such as passion flower, chamomile, Vitamin B1, and others.

Shop Now

The primary use of melatonin supplement for dogs is to treat anxiety, both that caused by a triggering event and chronic anxiety. Seeing your pet shiver and cower when there’s a storm or being witness to their everyday struggles when you go to work is not easy on the pet owner – even less so on the dog himself. Finding a viable solution for your pet’s anxiety that’s not full of chemicals and comes with a serious list of side effects is not always easy, so it’s easy to see why melatonin for dogs is a popular alternative. 

In addition to its relaxing properties, melatonin for dogs has other uses as well. You can supplement melatonin to improve your pet’s sleeping patterns, help with seasonal hair alopecia (bald patches), or symptoms of Cushing’s disease if your dog has it. If you’re unsure if your dog could benefit from melatonin supplements, talk to your veterinarian. A professional that has your dog’s health record is the only one that can know for certainty which supplements are needed and which could do more harm than good. 

Melatonin is widely known as the sleep hormone- everyone knows that a healthy production of melatonin is required to regulate sleep patterns, but not many know that the same goes for our four-legged friends. Not unlike us, dogs rely on melatonin hormone to relax their body and mind enough to go to sleep, and that’s where its applicability in treating anxiety comes from. Even though your dog might be producing enough sleep hormone on his own, when melatonin is introduced through a supplement, it will have a calming effect on your pet. Studies have shown that the use of melatonin can increase GABA levels in the brains of animals, which is the same effect strong anxiety medications have (such as the benzodiazepine class of sedatives). In theory, this would mean that melatonin supplements for dogs offer a viable alternative for meds, but it’s important to consult your vet before trying anything on your own. Despite being a milder alternative, you can still overdose your pet on melatonin and cause adverse effects, so it’s best to be cautious when adding this supplement to your pet’s routine.

While melatonin for dogs can be an extremely beneficial supplement that improves the quality of your pet’s life, in this case, there can be too much of a good thing. Overdosing on melatonin is easier than you’d expect, and if you go overboard with the amount of melatonin supplement you’re giving to your pet, they could experience an array of side effects. The adverse effects that result from too much melatonin range from mild, that include drowsiness and vomiting, to more severe, such as lack of coordination, seizures, and high blood pressure. Luckily, it’s not common for pets to experience this, as it takes a lot of melatonin for a dog to overdose. Just make sure to stick to the recommended amount of supplements per day and you’ll be safe- also, be sure to keep your pet’s supplements out of his reach, just in case. 

Making sure your pet is getting the right kind of supplements is not always easy – they are not prescribed, so unless you get a concrete tip from your vet, you’ll be left to your own devices. Melatonin for dogs is available in various different formulas, many of which include different calming agents, too, so picking up a melatonin supplement is not a straightforward process. You will have to consider your pet’s unique situation and needs before you pick, and it will require a bit of research. There are many features to consider, from form to formula, before you make the purchase: here are some of the most important factors that could influence your decision:

  • Ingredients

More often than not, melatonin is just one of the ingredients in various supplements for dogs, although it can be given on its own where applicable. If you’re looking for calming dog supplements, there are dozens of different formulas, from those that include hemp to naturally relaxing herbs such as chamomile to boost the effects of melatonin. Before you settle on a specific anti-anxiety dog supplement, be sure to do some research and figure out which combination would do best for your pet’s needs. After all, there are many unique situations to consider: he might need something a bit more potent to soothe him or a supplement that’s suited for everyday use, etc.

In case you need melatonin for dogs due to its other beneficial properties, such as its effect on seasonal balding or to include in the treatment of epilepsy, it’s best to go for supplements that contain only melatonin. Just be sure to double-check if the dosage is right for your pet’s size – you don’t want to overdo it.

  • Potency

Regardless of the formula, the levels of melatonin in each supplement can vary greatly, and it’s important to check the doses to make sure your pet is getting enough to treat his health issues. Too little and the melatonin supplement will fail to deliver the promised benefits and too much and you risk serious adverse effects. Naturally, the dosage will depend on your pet’s weight and it can be particularly difficult to determine the exact amount your pet needs without consulting a veterinarian, especially if your pet is a small breed dog.

  • Delivery method

Not all doggos will gladly swallow everything you give them- even though their appetite might make you think differently. Dogs can be quite finicky when it comes to taking medicine, and supplements fall into that category. It might take some coaxing to get your pooch to cooperate! To minimize the hassle that administering melatonin can be, it’s smart to go for a delivery method that suits your pet the most. Melatonin for dogs is available in the form of pills and tablets, flavored chewables, liquids, powders, and even injections and subcutaneous implants. For most dogs, the most convenient options are chewables (in a flavor they love) or powdered and liquid supplements that are tasteless and can be mixed in with their food. 


We are committed to finding, researching, and recommending the best products. We earn commissions from purchases you make using the retail links in our product reviews. Learn more about how this works